189278
Sigma-Aldrich

P-TOLUENESULFONYL ISOCYAN

Linear Formula:

CH3C6H4SO2NCO

Empform:

C8H7NO3S

Synonyms English:

Tosyl isocyanate

Nacres: NA.22
Mdl No: MFCD00002030
Fw: 197.21
Pubchem Substance Id: 24851374
CAS Number: 4083-64-1
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Properties

Properties
assay 96%
bp 144 
bromine number ?C/10 
brush size diam. × l mmHg (lit.)
depth 1.291 
depth × h × w g/mL 
depth × overall h at 25 
depth × width ?C (lit.)
Description P-TOLUENESULFONYL ISOCYAN
frame w × l liquid
inlet and outlet nptm × nptm 1S/C8H7NO3S/c1-7-2-4-8(5-3-7)13(1112)9-6-10/h2-5H1H3
inlet and outlet size VLJQDHDVZJXNQL-UHFFFAOYSA-N
Need written commitment NI0000

Description

Application

p-Toluenesulfonyl isocyanate has been used as :
  • derivatization reagent in determination of 3-α-hydroxy tibolone in human plasma by LC-MS/MS
  • derivatization reagent in simultaneous quantitative analysis of diethylene glycol and propylene glycol in pharmaceutical products by HPLC
  • as reagent in the preparation of acetylated syn-1,2-diols, oxazolidin-2-ones, 2,3-diamino acids and N-tosylcarbonamides

General description

p-Toluenesulfonyl isocyanate undergoes palladium-catalyzed bis-allylation reaction with allylstannanes and allyl chlorides.

SAFETY INFORMATION

GHS07,GHS08

Signal Word

Danger

H315 - H319 - H334 - H335

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

RIDADRRIDADR

WGK Germany

WGK 1

Flash Point (F)

294.8 °F - closed cup

Flash Point (C)

146 °C - closed cup

Target Organs

Respiratory system

Risk Statement

Supplemental Hazard Statements

DOCUMENTATION

Certificate of Analysis View Sample COA
Certificate of Origin

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